Ohio State travels to Iowa in a Big Ten matchup that marks the Buckeyes' first trip to Kinnick Stadium since 2017, per multiple outlets. ESPN announced that "College GameDay" will be in Iowa City for the game. Hank Brown, in his first year as starting quarterback for the Hawkeyes, is coming off a game where he led Iowa to their first walkoff touchdown since 2009, according to reporting from Land-Grant Holy Life. Brown's strength lies in avoiding mistakes rather than putting up large offensive numbers.
Elsewhere in Week 5, Michigan plays Minnesota at noon on FOX for the Little Brown Jug, a rivalry trophy dating to 1903 when Fielding Yost's Wolverines left a five-gallon water jug behind following a 6-6 final at Minnesota. A top 25 SEC matchup between No. 7 Alabama and No. 16 Mississippi State is also on the schedule, while Penn State faces Northwestern.
In a late-night Big 12 showdown, unbeaten Cincinnati travels to Arizona. After four weeks, Arizona sits with the same record it had in each of the previous two seasons, per reporting from Yahoo Sports.