The Patriots will face the Bills on Sunday without two defensive starters. Christian Gonzalez and Christian Barmore have been ruled out for Week 4, per Mike Vrabel, the Patriots head coach.

Espn reported that both players are sidelined due to shoulder injuries. Gonzalez, a cornerback, missed the entire week of practice with his shoulder injury, per NFL Trade Rumors. Barmore plays defensive tackle for New England.

The Patriots will visit Buffalo on Sunday at Highmark Stadium.