San Francisco 49ers rookie wide receiver De'Zhaun Stribling suffered a left ankle injury early in Thursday night's game against the Rams and has been ruled out for the remainder of the contest. Per multiple reports, Stribling was carted off the field after the non-contact injury.

Stribling had been having a standout training camp heading into the season, per Yahoo Sports. One report from Niners Nation indicates he briefly returned to the game after initially leaving, though most accounts focus on his departure via cart to the locker room.

The injury continues what San Francisco has described as ongoing injury difficulties. The 49ers have historically ranked among the worst in the NFL in adjusted games lost due to injuries, a trend the team is experiencing again early in the 2026 season.