DJ Moore will not play for the Bills on Monday Night Football against the Rams, per Pro Football Talk. Moore was initially listed as questionable with a shoulder injury before being ruled out ahead of the game.
The Bills are also without cornerback Dee Alford, who is inactive for the matchup. Alford has logged 13 total tackles—11 assists and 2 solo—across four games this season.
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Buffalo enters Monday at 3-1 and in first place in the AFC East, but the team is coming off a 29-26 loss to New England on Sunday, Oct. 4. The loss snapped a two-game winning streak that included a 24-16 victory over the Chargers on Sept. 27 and a 41-31 win over Detroit on Sept. 17. Josh Allen and the offense will face a Rams defense led by Matthew Stafford, who has completed 99 of 162 passes for 1,189 yards and seven touchdowns through four games this season.
The Rams sit at 2-2 and third in the NFC West. Los Angeles won its last game, 24-20 at Philadelphia on Oct. 4, before the Bills game.
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